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Effects of dopamine D2/3 and opioid receptor antagonism on the trade-off between model-based and model-free behaviour in healthy volunteers

Human behaviour requires flexible arbitration between actions we do out of habit and actions that are directed towards a specific goal. Drugs that target opioid and dopamine receptors are notorious for inducing maladaptive habitual drug consumption; yet, how the opioidergic and dopaminergic neurotra...

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Detalles Bibliográficos
Autores principales: Mikus, Nace, Korb, Sebastian, Massaccesi, Claudia, Gausterer, Christian, Graf, Irene, Willeit, Matthäus, Eisenegger, Christoph, Lamm, Claus, Silani, Giorgia, Mathys, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9721617/
https://www.ncbi.nlm.nih.gov/pubmed/36468832
http://dx.doi.org/10.7554/eLife.79661