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DLL3 regulates Notch signaling in small cell lung cancer

Tumor heterogeneity plays a critical role in tumor development and response to treatment. In small-cell lung cancer (SCLC), intratumoral heterogeneity is driven in part by the Notch signaling pathway, which reprograms neuroendocrine cancer cells to a less/non-neuroendocrine state. Here we investigat...

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Detalles Bibliográficos
Autores principales: Kim, Jun W., Ko, Julie H., Sage, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722452/
https://www.ncbi.nlm.nih.gov/pubmed/36483011
http://dx.doi.org/10.1016/j.isci.2022.105603