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The SNARE protein SNAP-25 is required for normal exocytosis at auditory hair cell ribbon synapses

Hearing depends on fast and sustained calcium-dependent synaptic vesicle fusion at the ribbon synapses of cochlear inner hair cells (IHCs). The implication of the canonical neuronal SNARE complex in this exocytotic process has so far remained controversial. We investigated the role of SNAP-25, a key...

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Detalles Bibliográficos
Autores principales: Calvet, Charlotte, Peineau, Thibault, Benamer, Najate, Cornille, Maxence, Lelli, Andrea, Plion, Baptiste, Lahlou, Ghizlène, Fanchette, Julia, Nouaille, Sylvie, Boutet de Monvel, Jacques, Estivalet, Amrit, Jean, Philippe, Michel, Vincent, Sachse, Martin, Michalski, Nicolas, Avan, Paul, Petit, Christine, Dulon, Didier, Safieddine, Saaid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722480/
https://www.ncbi.nlm.nih.gov/pubmed/36483015
http://dx.doi.org/10.1016/j.isci.2022.105628