Cocaine sensitizes the CD4(+) T cells for HIV infection by co-stimulating NFAT and AP-1

The productive infection of HIV, which generates new viral progeny, depends on the activation status of the cell. In this study, we found cocaine exposure sensitizes partially active CD4(+) T cells and makes them poised for productive HIV infection. We discovered that cocaine treatment enhances the...

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Detalles Bibliográficos
Autores principales: Sharma, Adhikarimayum Lakhikumar, Shaffer, Dylan, Netting, Daniel, Tyagi, Mudit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722482/
https://www.ncbi.nlm.nih.gov/pubmed/36483012
http://dx.doi.org/10.1016/j.isci.2022.105651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722482/
https://www.ncbi.nlm.nih.gov/pubmed/36483012
http://dx.doi.org/10.1016/j.isci.2022.105651

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