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Cocaine sensitizes the CD4(+) T cells for HIV infection by co-stimulating NFAT and AP-1
The productive infection of HIV, which generates new viral progeny, depends on the activation status of the cell. In this study, we found cocaine exposure sensitizes partially active CD4(+) T cells and makes them poised for productive HIV infection. We discovered that cocaine treatment enhances the...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722482/ https://www.ncbi.nlm.nih.gov/pubmed/36483012 http://dx.doi.org/10.1016/j.isci.2022.105651 |