KLF4-PFKFB3-driven glycolysis is essential for phenotypic switching of vascular smooth muscle cells

Vascular smooth muscle cells (VSMCs) within atherosclerotic lesions undergo a phenotypic switching in a KLF4-dependent manner. Glycolysis plays important roles in transdifferentiation of somatic cells, however, it is unclear whether and how KLF4 mediates the link between glycolytic switch and VSMCs...

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Detalles Bibliográficos
Autores principales: Zhang, Xinhua, Zheng, Bin, Zhao, Lingdan, Shen, Jiayi, Yang, Zhan, Zhang, Yu, Fan, Ruirui, Zhang, Manli, Ma, Dong, Zheng, Lemin, Zhao, Mingming, Liu, Huirong, Wen, Jinkun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722670/
https://www.ncbi.nlm.nih.gov/pubmed/36470917
http://dx.doi.org/10.1038/s42003-022-04302-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722670/
https://www.ncbi.nlm.nih.gov/pubmed/36470917
http://dx.doi.org/10.1038/s42003-022-04302-y

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