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Non-genetic adaptive resistance to KRAS(G12C) inhibition: EMT is not the only culprit
Adaptions to therapeutic pressures exerted on cancer cells enable malignant progression of the tumor, culminating in escape from programmed cell death and development of resistant diseases. A common form of cancer adaptation is non-genetic alterations that exploit mechanisms already present in cance...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722758/ https://www.ncbi.nlm.nih.gov/pubmed/36483040 http://dx.doi.org/10.3389/fonc.2022.1004669 |