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Non-genetic adaptive resistance to KRAS(G12C) inhibition: EMT is not the only culprit

Adaptions to therapeutic pressures exerted on cancer cells enable malignant progression of the tumor, culminating in escape from programmed cell death and development of resistant diseases. A common form of cancer adaptation is non-genetic alterations that exploit mechanisms already present in cance...

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Detalles Bibliográficos
Autores principales:	Ning, Wenjuan, Marti, Thomas M., Dorn, Patrick, Peng, Ren-Wang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722758/ https://www.ncbi.nlm.nih.gov/pubmed/36483040 http://dx.doi.org/10.3389/fonc.2022.1004669

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