CRISPR/Cas9-mediated abrogation of CD95L/CD95 signaling-induced glioma cell growth and immunosuppression increases survival in murine glioma models

PURPOSE: Glioblastoma is the most common brain tumor in adults and is virtually incurable. Therefore, new therapeutic strategies are urgently needed. Over the last decade, multiple growth-promoting functions have been attributed to CD95, a prototypic death receptor well characterized as an apoptosis...

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Detalles Bibliográficos
Autores principales: Quijano-Rubio, Clara, Silginer, Manuela, Weller, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722998/
https://www.ncbi.nlm.nih.gov/pubmed/36355258
http://dx.doi.org/10.1007/s11060-022-04137-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9722998/
https://www.ncbi.nlm.nih.gov/pubmed/36355258
http://dx.doi.org/10.1007/s11060-022-04137-x

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