Anti-PD-L1/PD-L2 therapeutic vaccination in untreated chronic lymphocytic leukemia patients with unmutated IgHV

Chronic lymphocytic leukemia (CLL) patients with unmutated immunoglobulin heavy chain (IgHV) are at risk of early disease progression compared to patients with mutated IgHV. As a preventive strategy, we treated 19 previously untreated CLL patients with unmutated IgHV in a phase 1/2 trial (clinicaltr...

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Detalles Bibliográficos
Autores principales: Klausen, Uffe, Grauslund, Jacob Handlos, Jørgensen, Nicolai Grønne Dahlager, Ahmad, Shamaila Munir, Jonassen, Merete, Weis-Banke, Stine Emilie, Martinenaite, Evelina, Pedersen, Lone Bredo, Lisle, Thomas Landkildehus, Gang, Anne Ortved, Enggaard, Lisbeth, Hansen, Morten, Holmström, Morten Orebo, Met, Özcan, Svane, Inge Marie, Niemann, Carsten Utoft, Pedersen, Lars Møller, Andersen, Mads Hald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723164/
https://www.ncbi.nlm.nih.gov/pubmed/36483037
http://dx.doi.org/10.3389/fonc.2022.1023015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723164/
https://www.ncbi.nlm.nih.gov/pubmed/36483037
http://dx.doi.org/10.3389/fonc.2022.1023015

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