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The mitochondrial unfolded protein response (UPR(mt)) protects against osteoarthritis

The mitochondrial unfolded protein response (UPR(mt)) is a mitochondrial-to-nuclear signaling pathway that is activated to maintain mitochondrial function when there is an accumulation of misfolded proteins within mitochondria. Mitochondrial function is essential for chondrocyte homeostasis, and mit...

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Detalles Bibliográficos
Autores principales: Zhou, Zhibin, Lu, Jiajia, Yang, Mei, Cai, Jiao, Fu, Qiang, Ma, Jun, Zhu, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723171/
https://www.ncbi.nlm.nih.gov/pubmed/36380018
http://dx.doi.org/10.1038/s12276-022-00885-y