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The mitochondrial unfolded protein response (UPR(mt)) protects against osteoarthritis
The mitochondrial unfolded protein response (UPR(mt)) is a mitochondrial-to-nuclear signaling pathway that is activated to maintain mitochondrial function when there is an accumulation of misfolded proteins within mitochondria. Mitochondrial function is essential for chondrocyte homeostasis, and mit...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723171/ https://www.ncbi.nlm.nih.gov/pubmed/36380018 http://dx.doi.org/10.1038/s12276-022-00885-y |