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The deubiquitinating enzyme STAMBP is a newly discovered driver of triple-negative breast cancer progression that maintains RAI14 protein stability

Triple-negative breast cancer (TNBC) is a heterogeneous malignancy in women. It is associated with poor prognosis, aggressive malignant behavior, and limited treatment options. In the ubiquitin‒proteasome system (UPS), deubiquitinases (DUBs) are potential therapeutic targets for various tumors. In t...

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Detalles Bibliográficos
Autores principales: Yang, Qianqian, Yan, Ding, Zou, Chaoying, Xue, Qian, Lin, Shuhui, Huang, Qingtian, Li, Xiaofen, Tang, Daolin, Chen, Xin, Liu, Jinbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723177/
https://www.ncbi.nlm.nih.gov/pubmed/36434041
http://dx.doi.org/10.1038/s12276-022-00890-1