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Lnc Tmem235 promotes repair of early steroid-induced osteonecrosis of the femoral head by inhibiting hypoxia-induced apoptosis of BMSCs

Bone marrow mesenchymal stem cells (BMSCs) have been used in the treatment of early steroid-induced osteonecrosis of the femoral head (SONFH). However, the hypoxic microenvironment in the osteonecrotic area leads to hypoxia-induced apoptosis of transplanted BMSCs, which limits their efficacy. Theref...

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Detalles Bibliográficos
Autores principales: Zhang, Fei, Peng, Wuxun, Wang, Tao, Zhang, Jian, Dong, Wentao, Wang, Chuan, Xie, Zhihong, Luo, Hong, Liu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723185/
https://www.ncbi.nlm.nih.gov/pubmed/36380019
http://dx.doi.org/10.1038/s12276-022-00875-0