Effects of intestinal microbiota on pharmacokinetics of cyclosporine a in rats

BACKGROUND: Intestinal microbiota has been confirmed to influencing the pharmacokinetic processes of a variety of oral drugs. However, the pharmacokinetic effects of the gut microbiota on cyclosporine A, a drug with a narrow therapeutic window, remain to be studied. METHOD: Twenty-one rats were rand...

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Detalles Bibliográficos
Autores principales: Zhou, Jinping, Zhang, Rui, Guo, Pengpeng, Li, Peixia, Huang, Xixi, Wei, Ye, Yang, Chunxiao, Zhou, Jiali, Yang, Tingyu, Liu, Yani, Shi, Shaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723225/
https://www.ncbi.nlm.nih.gov/pubmed/36483198
http://dx.doi.org/10.3389/fmicb.2022.1032290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723225/
https://www.ncbi.nlm.nih.gov/pubmed/36483198
http://dx.doi.org/10.3389/fmicb.2022.1032290

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