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Multiplexed engineering and precision gene editing in cellular immunotherapy

The advent of cellular immunotherapy in the clinic has entirely redrawn the treatment landscape for a growing number of human cancers. Genetically reprogrammed immune cells, including chimeric antigen receptor (CAR)-modified immune effector cells as well as T cell receptor (TCR) therapy, have demons...

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Detalles Bibliográficos
Autores principales: Biederstädt, Alexander, Manzar, Gohar Shahwar, Daher, May
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723254/
https://www.ncbi.nlm.nih.gov/pubmed/36483551
http://dx.doi.org/10.3389/fimmu.2022.1063303