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ALD-R491 regulates vimentin filament stability and solubility, cell contractile force, cell migration speed and directionality

Metastasizing cells express the intermediate filament protein vimentin, which is used to diagnose invasive tumors in the clinic. However, the role of vimentin in cell motility, and if the assembly of non-filamentous variants of vimentin into filaments regulates cell migration remains unclear. We obs...

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Detalles Bibliográficos
Autores principales: Kim, Hyejeong Rosemary, Warrington, Samantha J., López-Guajardo, Ana, Al Hennawi, Khairat, Cook, Sarah L., Griffith, Zak D. J., Symmes, Deebie, Zhang, Tao, Qu, Zhipeng, Xu, Ying, Chen, Ruihuan, Gad, Annica K. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723350/
https://www.ncbi.nlm.nih.gov/pubmed/36483676
http://dx.doi.org/10.3389/fcell.2022.926283