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Are homeostatic mechanisms aiding the reconstitution of the T-cell pool during lymphopenia in humans?

A timely recovery of T-cell numbers following haematopoietic stem-cell transplantation (HSCT) is essential for preventing complications, such as increased risk of infection and disease relapse. In analogy to the occurrence of lymphopenia-induced proliferation in mice, T-cell dynamics in humans are t...

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Detalles Bibliográficos
Autores principales: Baliu-Piqué, Mariona, Tesselaar, Kiki, Borghans, José A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723355/
https://www.ncbi.nlm.nih.gov/pubmed/36483556
http://dx.doi.org/10.3389/fimmu.2022.1059481