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TLsub: A transfer learning based enhancement to accurately detect mutations with wide-spectrum sub-clonal proportion

Mutation detecting is a routine work for sequencing data analysis and the trading of existing tools often involves the combinations of signals on a set of overlapped sequencing reads. However, the subclonal mutations, which are reported to contribute to tumor recurrence and metastasis, are sometimes...

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Detalles Bibliográficos
Autor principal: Zheng, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723383/
https://www.ncbi.nlm.nih.gov/pubmed/36482899
http://dx.doi.org/10.3389/fgene.2022.981269