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TLsub: A transfer learning based enhancement to accurately detect mutations with wide-spectrum sub-clonal proportion
Mutation detecting is a routine work for sequencing data analysis and the trading of existing tools often involves the combinations of signals on a set of overlapped sequencing reads. However, the subclonal mutations, which are reported to contribute to tumor recurrence and metastasis, are sometimes...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723383/ https://www.ncbi.nlm.nih.gov/pubmed/36482899 http://dx.doi.org/10.3389/fgene.2022.981269 |