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CaMKIV mediates spine growth deficiency of hippocampal neurons by regulation of EGR3/BDNF signal axis in congenital hypothyroidism

Congenital hypothyroidism (CH) will cause cognitive impairment in the condition of delayed treatment. The hippocampus is one of the most affected tissues by CH, in which the functional structures of hippocampal neurons manifest deficiency due to aberrant expression of effector molecules. The Ca(2+)/...

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Detalles Bibliográficos
Autores principales: Wu, Hui, Suo, Guihai, Li, Tianci, Zheng, Yuqin, Li, Haiying, Shen, Feifei, Wang, Yongjun, Ni, Haidong, Wu, Youjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723595/
https://www.ncbi.nlm.nih.gov/pubmed/36473844
http://dx.doi.org/10.1038/s41420-022-01270-4