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CaMKIV mediates spine growth deficiency of hippocampal neurons by regulation of EGR3/BDNF signal axis in congenital hypothyroidism
Congenital hypothyroidism (CH) will cause cognitive impairment in the condition of delayed treatment. The hippocampus is one of the most affected tissues by CH, in which the functional structures of hippocampal neurons manifest deficiency due to aberrant expression of effector molecules. The Ca(2+)/...
Autores principales: | Wu, Hui, Suo, Guihai, Li, Tianci, Zheng, Yuqin, Li, Haiying, Shen, Feifei, Wang, Yongjun, Ni, Haidong, Wu, Youjia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723595/ https://www.ncbi.nlm.nih.gov/pubmed/36473844 http://dx.doi.org/10.1038/s41420-022-01270-4 |
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