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Deep learning-assisted genome-wide characterization of massively parallel reporter assays

Massively parallel reporter assay (MPRA) is a high-throughput method that enables the study of the regulatory activities of tens of thousands of DNA oligonucleotides in a single experiment. While MPRA experiments have grown in popularity, their small sample sizes compared to the scale of the human g...

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Detalles Bibliográficos
Autores principales: Lu, Fred, Sossin, Aaron, Abell, Nathan, Montgomery, Stephen B, He, Zihuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723615/
https://www.ncbi.nlm.nih.gov/pubmed/36350674
http://dx.doi.org/10.1093/nar/gkac990