An updated definition of V(D)J recombination signal sequences revealed by high-throughput recombination assays

In the adaptive immune system, V(D)J recombination initiates the production of a diverse antigen receptor repertoire in developing B and T cells. Recombination activating proteins, RAG1 and RAG2 (RAG1/2), catalyze V(D)J recombination by cleaving adjacent to recombination signal sequences (RSSs) that...

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Detalles Bibliográficos
Autores principales: Hoolehan, Walker, Harris, Justin C, Byrum, Jennifer N, Simpson, Destiny A, Rodgers, Karla K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723617/
https://www.ncbi.nlm.nih.gov/pubmed/36370096
http://dx.doi.org/10.1093/nar/gkac1038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723617/
https://www.ncbi.nlm.nih.gov/pubmed/36370096
http://dx.doi.org/10.1093/nar/gkac1038

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