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Accurate measurement of microsatellite length by disrupting its tandem repeat structure

Tandem repeats of simple sequence motifs, also known as microsatellites, are abundant in the genome. Because their repeat structure makes replication error-prone, variant microsatellite lengths are often generated during germline and other somatic expansions. As such, microsatellite length variation...

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Detalles Bibliográficos
Autores principales: Wang, Zihua, Moffitt, Andrea B, Andrews, Peter, Wigler, Michael, Levy, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723644/
https://www.ncbi.nlm.nih.gov/pubmed/36095132
http://dx.doi.org/10.1093/nar/gkac723