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Mod(mdg4) variants repress telomeric retrotransposon HeT-A by blocking subtelomeric enhancers

Telomeres in Drosophila are composed of sequential non-LTR retrotransposons HeT-A, TART and TAHRE. Although they are repressed by the PIWI-piRNA pathway or heterochromatin in the germline, the regulation of these retrotransposons in somatic cells is poorly understood. In this study, we demonstrated...

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Detalles Bibliográficos
Autores principales: Takeuchi, Chikara, Yokoshi, Moe, Kondo, Shu, Shibuya, Aoi, Saito, Kuniaki, Fukaya, Takashi, Siomi, Haruhiko, Iwasaki, Yuka W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723646/
https://www.ncbi.nlm.nih.gov/pubmed/36373634
http://dx.doi.org/10.1093/nar/gkac1034