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Ecological effects of stress drive bacterial evolvability under sub-inhibitory antibiotic treatments

Stress is thought to increase mutation rate and thus to accelerate evolution. In the context of antibiotic resistance, sub-inhibitory treatments could then lead to enhanced evolvability, thereby fuelling the adaptation of pathogens. Combining wet-lab experiments, stochastic simulations and a meta-an...

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Detalles Bibliográficos
Autores principales: Vasse, Marie, Bonhoeffer, Sebastian, Frenoy, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723650/
https://www.ncbi.nlm.nih.gov/pubmed/37938266
http://dx.doi.org/10.1038/s43705-022-00157-w