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Ecological effects of stress drive bacterial evolvability under sub-inhibitory antibiotic treatments
Stress is thought to increase mutation rate and thus to accelerate evolution. In the context of antibiotic resistance, sub-inhibitory treatments could then lead to enhanced evolvability, thereby fuelling the adaptation of pathogens. Combining wet-lab experiments, stochastic simulations and a meta-an...
Autores principales: | Vasse, Marie, Bonhoeffer, Sebastian, Frenoy, Antoine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723650/ https://www.ncbi.nlm.nih.gov/pubmed/37938266 http://dx.doi.org/10.1038/s43705-022-00157-w |
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