Differential contributions of the proteasome, autophagy, and chaperones to the clearance of arsenite-induced protein aggregates in yeast

The poisonous metalloid arsenite induces widespread misfolding and aggregation of nascent proteins in vivo, and this mode of toxic action might underlie its suspected role in the pathology of certain protein misfolding diseases. Evolutionarily conserved protein quality-control systems protect cells...

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Detalles Bibliográficos
Autores principales: Hua, Sansan, Kłosowska, Agnieszka, Rodrigues, Joana I., Petelski, Gabriel, Esquembre, Lidia A., Lorentzon, Emma, Olsen, Lars F., Liberek, Krzysztof, Tamás, Markus J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723941/
https://www.ncbi.nlm.nih.gov/pubmed/36356902
http://dx.doi.org/10.1016/j.jbc.2022.102680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723941/
https://www.ncbi.nlm.nih.gov/pubmed/36356902
http://dx.doi.org/10.1016/j.jbc.2022.102680

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