T cells of colorectal cancer patients’ stimulated by neoantigenic and cryptic peptides better recognize autologous tumor cells

BACKGROUND: Patients with cancers that exhibit extraordinarily high somatic mutation numbers are ideal candidates for immunotherapy and enable identifying tumor-specific peptides through stimulation of tumor-reactive T cells (Tc). METHODS: Colorectal cancers (CRC) HROC113 and HROC285 were selected b...

Descripción completa

Detalles Bibliográficos
Autores principales: Schwarz, Sandra, Schmitz, Johanna, Löffler, Markus W, Ghosh, Michael, Rammensee, Hans-Georg, Olshvang, Evgenia, Markel, Marvin, Mockel-Tenbrinck, Nadine, Dzionek, Andrzej, Krake, Susann, Arslan, Basak, Kampe, Kapil Dev, Wendt, Anne, Bauer, Peter, Mullins, Christina S, Schlosser, Andreas, Linnebacher, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723954/
https://www.ncbi.nlm.nih.gov/pubmed/36460334
http://dx.doi.org/10.1136/jitc-2022-005651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723954/
https://www.ncbi.nlm.nih.gov/pubmed/36460334
http://dx.doi.org/10.1136/jitc-2022-005651

Ejemplares similares