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T cells of colorectal cancer patients’ stimulated by neoantigenic and cryptic peptides better recognize autologous tumor cells

BACKGROUND: Patients with cancers that exhibit extraordinarily high somatic mutation numbers are ideal candidates for immunotherapy and enable identifying tumor-specific peptides through stimulation of tumor-reactive T cells (Tc). METHODS: Colorectal cancers (CRC) HROC113 and HROC285 were selected b...

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Detalles Bibliográficos
Autores principales:	Schwarz, Sandra, Schmitz, Johanna, Löffler, Markus W, Ghosh, Michael, Rammensee, Hans-Georg, Olshvang, Evgenia, Markel, Marvin, Mockel-Tenbrinck, Nadine, Dzionek, Andrzej, Krake, Susann, Arslan, Basak, Kampe, Kapil Dev, Wendt, Anne, Bauer, Peter, Mullins, Christina S, Schlosser, Andreas, Linnebacher, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723954/ https://www.ncbi.nlm.nih.gov/pubmed/36460334 http://dx.doi.org/10.1136/jitc-2022-005651

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