Development of (89)Zr-anti-CD103 PET imaging for non-invasive assessment of cancer reactive T cell infiltration

PURPOSE: CD103, an integrin specifically expressed on the surface of cancer-reactive T cells, is significantly increased during successful immunotherapy across human malignancies. In this study, we describe the generation and zirconium-89 ((89)Zr) radiolabeling of monoclonal antibody (mAb) clones th...

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Detalles Bibliográficos
Autores principales: Kol, Arjan, Fan, Xiaoyu, Wazynska, Marta A., van Duijnhoven, Sander M.J., Giesen, Danique, Plat, Annechien, Van Eenennaam, Hans, Elsinga, Philip H., Nijman, Hans W., de Bruyn, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Immunotherapy Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723959/
https://www.ncbi.nlm.nih.gov/pubmed/36600560
http://dx.doi.org/10.1136/jitc-2022-004877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9723959/
https://www.ncbi.nlm.nih.gov/pubmed/36600560
http://dx.doi.org/10.1136/jitc-2022-004877

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