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Skeletal Ring Contractions via I(I)/I(III) Catalysis: Stereoselective Synthesis of cis-α,α-Difluorocyclopropanes

[Image: see text] The clinical success of α,α-difluorocyclopropanes, combined with limitations in the existing synthesis portfolio, inspired the development of an operationally simple, organocatalysis-based strategy to access cis-configured derivatives with high levels of stereoselectivity (up to &g...

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Detalles Bibliográficos
Autores principales: Livingstone, Keith, Siebold, Kathrin, Meyer, Stephanie, Martín-Heras, Víctor, Daniliuc, Constantin G., Gilmour, Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724094/
https://www.ncbi.nlm.nih.gov/pubmed/36504915
http://dx.doi.org/10.1021/acscatal.2c04511