Cargando…
Skeletal Ring Contractions via I(I)/I(III) Catalysis: Stereoselective Synthesis of cis-α,α-Difluorocyclopropanes
[Image: see text] The clinical success of α,α-difluorocyclopropanes, combined with limitations in the existing synthesis portfolio, inspired the development of an operationally simple, organocatalysis-based strategy to access cis-configured derivatives with high levels of stereoselectivity (up to &g...
Autores principales: | Livingstone, Keith, Siebold, Kathrin, Meyer, Stephanie, Martín-Heras, Víctor, Daniliuc, Constantin G., Gilmour, Ryan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724094/ https://www.ncbi.nlm.nih.gov/pubmed/36504915 http://dx.doi.org/10.1021/acscatal.2c04511 |
Ejemplares similares
-
Difluorination of α-(bromomethyl)styrenes via I(I)/I(III) catalysis: facile access to electrophilic linchpins for drug discovery
por: Häfliger, Joel, et al.
Publicado: (2021) -
para-Selective dearomatization of phenols by I(i)/I(iii) catalysis-based fluorination
por: Stünkel, Timo, et al.
Publicado: (2023) -
Fluorohydration of alkynes via I(I)/I(III) catalysis
por: Neufeld, Jessica, et al.
Publicado: (2020) -
Fluorocyclisation via I(I)/I(III) catalysis: a concise route to fluorinated oxazolines
por: Scheidt, Felix, et al.
Publicado: (2018) -
Integrating I(I)/I(III) catalysis in reaction cascade design enables the synthesis of gem-difluorinated tetralins from cyclobutanols
por: Häfliger, Joel, et al.
Publicado: (2023)