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High-mobility Group Box 1 Contributes to Hypoxic-Ischemic Brain Damage by Facilitating Imbalance of Microglial Polarization through RAGE-PI3K/Akt Pathway in Neonatal Rats

High mobility group box 1 (HMGB1) is a damage-associated molecular pattern integral for hypoxic-ischemic brain damage (HIBD) in neonatal rats since it regulates the phenotypic polarization of microglia, as depicted in our previous studies. Since this mechanism is not clear, this study establishes an...

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Detalles Bibliográficos
Autores principales: Sun, Yanyan, Zhu, Xing, Zhu, Kaiyi, Yu, Jie, Cheng, Lin, Hei, Mingyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724240/
https://www.ncbi.nlm.nih.gov/pubmed/36483598
http://dx.doi.org/10.7150/ijms.78641