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Reconstruction of the gastric cancer microenvironment after neoadjuvant chemotherapy by longitudinal single-cell sequencing

BACKGROUND: Little is known on the tumor microenvironment (TME) response after neoadjuvant chemotherapy (NACT) in gastric cancer on the molecular level. METHODS: Here, we profiled 33,589 cell transcriptomes in 14 samples from 11 gastric cancer patients (4 pre-treatment samples, 4 post-treatment samp...

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Detalles Bibliográficos
Autores principales: Chen, Yingtai, Yin, Jianhua, Zhao, Lulu, Zhou, Guangyu, Dong, Shichen, Zhang, Yueming, Niu, Penghui, Ren, Hu, Zheng, Tianjiao, Yan, Juan, Li, Wenbin, Ma, Peiqin, Zhang, Cuijuan, Wei, Chen, Church, George, Li, Guibo, Zhao, Dongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724296/
https://www.ncbi.nlm.nih.gov/pubmed/36474268
http://dx.doi.org/10.1186/s12967-022-03792-y