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Expression of hub genes of endothelial cells in glioblastoma-A prognostic model for GBM patients integrating single-cell RNA sequencing and bulk RNA sequencing

BACKGROUND: This study aimed to use single-cell RNA-seq (scRNA-seq) to discover marker genes in endothelial cells (ECs) and construct a prognostic model for glioblastoma multiforme (GBM) patients in combination with traditional high-throughput RNA sequencing (bulk RNA-seq). METHODS: Bulk RNA-seq dat...

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Detalles Bibliográficos
Autores principales: Zhao, Songyun, Ji, Wei, Shen, Yifan, Fan, Yuansheng, Huang, Hui, Huang, Jin, Lai, Guichuan, Yuan, Kemiao, Cheng, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724299/
https://www.ncbi.nlm.nih.gov/pubmed/36474171
http://dx.doi.org/10.1186/s12885-022-10305-z