Interruption of the long non-coding RNA HOTAIR signaling axis ameliorates chemotherapy-induced cachexia in bladder cancer

BACKGROUND: Cisplatin-based chemotherapy is the first line of treatment for bladder cancer. However, cisplatin induces muscle wasting associated with NF-κB and cancer cachexia. HOTAIR, an oncogenic long non-coding RNA (lncRNA), promotes cancer progression in different cancers. Crosstalk between HOTA...

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Detalles Bibliográficos
Autores principales: Hu, Che-Yuan, Su, Bing-Hua, Lee, Ya-Che, Wang, Chung-Teng, Yang, Mei-Lin, Shen, Wan-Ting, Fu, Jing-Ting, Chen, Shih-Yao, Huang, Wei-Yun, Ou, Chien-Hui, Tsai, Yuh-Shyan, Kuo, Feng-Chih, Shiau, Ai-Li, Shieh, Gia-Shing, Wu, Chao-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724340/
https://www.ncbi.nlm.nih.gov/pubmed/36471329
http://dx.doi.org/10.1186/s12929-022-00887-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724340/
https://www.ncbi.nlm.nih.gov/pubmed/36471329
http://dx.doi.org/10.1186/s12929-022-00887-y

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