PACAP signaling is not involved in GTN- and levcromakalim-induced hypersensitivity in mouse models of migraine

BACKGROUND: Calcitonin gene-related peptide (CGRP) antagonizing drugs represents the most important advance in migraine therapy for decades. However, these new drugs are only effective in 50–60% of patients. Recent studies have shown that the pituitary adenylate cyclase-activating peptide (PACAP38)...

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Detalles Bibliográficos
Autores principales: Guo, Song, Ernstsen, Charlotte, Hay-Schmidt, Anders, Kristensen, David Møbjerg, Ashina, Messoud, Olesen, Jes, Christensen, Sarah Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724374/
https://www.ncbi.nlm.nih.gov/pubmed/36471250
http://dx.doi.org/10.1186/s10194-022-01523-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724374/
https://www.ncbi.nlm.nih.gov/pubmed/36471250
http://dx.doi.org/10.1186/s10194-022-01523-8

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