GCN5L1-mediated TFAM acetylation at K76 participates in mitochondrial biogenesis in acute kidney injury

BACKGROUND: Mitochondrial dysfunction is an important pathogenic event in acute kidney injury (AKI). GCN5L1 is a specific acetyltransferase in mitochondria, which regulates glucose and fatty acid metabolism. However, the role of GCN5L1 in mitochondrial dysfunction and the pathogenesis of ischemic AK...

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Detalles Bibliográficos
Autores principales: Lv, Tingting, Zhang, Yu, Ji, XingZhao, Sun, Shengnan, Xu, Li, Ma, Weixia, Liu, Yi, Wan, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724393/
https://www.ncbi.nlm.nih.gov/pubmed/36474281
http://dx.doi.org/10.1186/s12967-022-03782-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724393/
https://www.ncbi.nlm.nih.gov/pubmed/36474281
http://dx.doi.org/10.1186/s12967-022-03782-0

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