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Identification of multiplicatively acting modulatory mutational signatures in cancer

BACKGROUND: A deep understanding of carcinogenesis at the DNA level underpins many advances in cancer prevention and treatment. Mutational signatures provide a breakthrough conceptualisation, as well as an analysis framework, that can be used to build such understanding. They capture somatic mutatio...

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Detalles Bibliográficos
Autores principales: Kičiatovas, Dovydas, Guo, Qingli, Kailas, Miika, Pesonen, Henri, Corander, Jukka, Kaski, Samuel, Pitkänen, Esa, Mustonen, Ville
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724449/
https://www.ncbi.nlm.nih.gov/pubmed/36474143
http://dx.doi.org/10.1186/s12859-022-05060-8