Cargando…
Identification of multiplicatively acting modulatory mutational signatures in cancer
BACKGROUND: A deep understanding of carcinogenesis at the DNA level underpins many advances in cancer prevention and treatment. Mutational signatures provide a breakthrough conceptualisation, as well as an analysis framework, that can be used to build such understanding. They capture somatic mutatio...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724449/ https://www.ncbi.nlm.nih.gov/pubmed/36474143 http://dx.doi.org/10.1186/s12859-022-05060-8 |