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Urine metabolomics and microbiome analyses reveal the mechanism of anti-tuberculosis drug-induced liver injury, as assessed for causality using the updated RUCAM: A prospective study

BACKGROUND: Anti-tuberculosis drug-induced liver injury (ATB-DILI) is one of the most common adverse reactions that brings great difficulties to the treatment of tuberculosis. Thus, early identification of individuals at risk for ATB-DILI is urgent. We conducted a prospective cohort study to analyze...

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Detalles Bibliográficos
Autores principales: Wang, Ming-Gui, Wu, Shou-Quan, Zhang, Meng-Meng, He, Jian-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724621/
https://www.ncbi.nlm.nih.gov/pubmed/36483548
http://dx.doi.org/10.3389/fimmu.2022.1002126