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Parkin drives pS65‐Ub turnover independently of canonical autophagy in Drosophila

Parkinson's disease‐related proteins, PINK1 and Parkin, act in a common pathway to maintain mitochondrial quality control. While the PINK1‐Parkin pathway can promote autophagic mitochondrial turnover (mitophagy) following mitochondrial toxification in cell culture, alternative quality control p...

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Detalles Bibliográficos
Autores principales: Usher, Joanne L, Sanchez‐Martinez, Alvaro, Terriente‐Felix, Ana, Chen, Po‐Lin, Lee, Juliette J, Chen, Chun‐Hong, Whitworth, Alexander J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724668/
https://www.ncbi.nlm.nih.gov/pubmed/36250243
http://dx.doi.org/10.15252/embr.202153552