Cargando…
Parkin drives pS65‐Ub turnover independently of canonical autophagy in Drosophila
Parkinson's disease‐related proteins, PINK1 and Parkin, act in a common pathway to maintain mitochondrial quality control. While the PINK1‐Parkin pathway can promote autophagic mitochondrial turnover (mitophagy) following mitochondrial toxification in cell culture, alternative quality control p...
Autores principales: | Usher, Joanne L, Sanchez‐Martinez, Alvaro, Terriente‐Felix, Ana, Chen, Po‐Lin, Lee, Juliette J, Chen, Chun‐Hong, Whitworth, Alexander J |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724668/ https://www.ncbi.nlm.nih.gov/pubmed/36250243 http://dx.doi.org/10.15252/embr.202153552 |
Ejemplares similares
-
Drosophila phosphatidylinositol-4 kinase fwd promotes mitochondrial fission and can suppress Pink1/parkin phenotypes
por: Terriente-Felix, Ana, et al.
Publicado: (2020) -
Basal mitophagy is widespread in Drosophila but minimally affected by loss of Pink1 or parkin
por: Lee, Juliette J., et al.
Publicado: (2018) -
Superoxide dismutating molecules rescue the toxic effects of PINK1 and parkin loss
por: Biosa, Alice, et al.
Publicado: (2018) -
The STING pathway does not contribute to behavioural or mitochondrial phenotypes in Drosophila Pink1/parkin or mtDNA mutator models
por: Lee, Juliette J., et al.
Publicado: (2020) -
Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation
por: Condos, Tara EC, et al.
Publicado: (2018)