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DDX60 selectively reduces translation off viral type II internal ribosome entry sites

Co‐opting host cell protein synthesis is a hallmark of many virus infections. In response, certain host defense proteins limit mRNA translation globally, albeit at the cost of the host cell's own protein synthesis. Here, we describe an interferon‐stimulated helicase, DDX60, that decreases trans...

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Detalles Bibliográficos
Autores principales: Sadic, Mohammad, Schneider, William M, Katsara, Olga, Medina, Gisselle N, Fisher, Ashley, Mogulothu, Aishwarya, Yu, Yingpu, Gu, Meigang, de los Santos, Teresa, Schneider, Robert J, Dittmann, Meike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724679/
https://www.ncbi.nlm.nih.gov/pubmed/36256515
http://dx.doi.org/10.15252/embr.202255218