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DDX60 selectively reduces translation off viral type II internal ribosome entry sites
Co‐opting host cell protein synthesis is a hallmark of many virus infections. In response, certain host defense proteins limit mRNA translation globally, albeit at the cost of the host cell's own protein synthesis. Here, we describe an interferon‐stimulated helicase, DDX60, that decreases trans...
Autores principales: | Sadic, Mohammad, Schneider, William M, Katsara, Olga, Medina, Gisselle N, Fisher, Ashley, Mogulothu, Aishwarya, Yu, Yingpu, Gu, Meigang, de los Santos, Teresa, Schneider, Robert J, Dittmann, Meike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724679/ https://www.ncbi.nlm.nih.gov/pubmed/36256515 http://dx.doi.org/10.15252/embr.202255218 |
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