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Phosphoproteomic Analysis Defines BABAM1 as mTORC2 Downstream Effector Promoting DNA Damage Response in Glioblastoma Cells

[Image: see text] Glioblastoma (GBM) is a devastating primary brain cancer with a poor prognosis. GBM is associated with an abnormal mechanistic target of rapamycin (mTOR) signaling pathway, consisting of two distinct kinase complexes: mTORC1 and mTORC2. The complexes play critical roles in cell pro...

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Detalles Bibliográficos
Autores principales: Kalpongnukul, Nuttiya, Bootsri, Rungnapa, Wongkongkathep, Piriya, Kaewsapsak, Pornchai, Ariyachet, Chaiyaboot, Pisitkun, Trairak, Chantaravisoot, Naphat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724709/
https://www.ncbi.nlm.nih.gov/pubmed/36315652
http://dx.doi.org/10.1021/acs.jproteome.2c00240