Kinetic analysis of ternary and binary binding modes of the bispecific antibody emicizumab

The binding properties of bispecific antibodies (bsAb) are crucial for their function, especially when two antigens are targeted on the same cell surface. Dynamic interactions between each of the antibody’s arms and its cognate target cause the formation and decay of a biologically functional ternar...

Descripción completa

Detalles Bibliográficos
Autores principales: Mak, Stefanie, Marszal, Agnes, Matscheko, Nena, Rant, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724730/
https://www.ncbi.nlm.nih.gov/pubmed/36453702
http://dx.doi.org/10.1080/19420862.2022.2149053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724730/
https://www.ncbi.nlm.nih.gov/pubmed/36453702
http://dx.doi.org/10.1080/19420862.2022.2149053

Ejemplares similares