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Kinetic analysis of ternary and binary binding modes of the bispecific antibody emicizumab
The binding properties of bispecific antibodies (bsAb) are crucial for their function, especially when two antigens are targeted on the same cell surface. Dynamic interactions between each of the antibody’s arms and its cognate target cause the formation and decay of a biologically functional ternar...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9724730/ https://www.ncbi.nlm.nih.gov/pubmed/36453702 http://dx.doi.org/10.1080/19420862.2022.2149053 |