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Dihydroxyacetone suppresses mTOR nutrient signaling and induces mitochondrial stress in liver cells

Dihydroxyacetone (DHA) is the active ingredient in sunless tanning products and a combustion product from e-juices in electronic cigarettes (e-cigarettes). DHA is rapidly absorbed in cells and tissues and incorporated into several metabolic pathways through its conversion to dihydroxyacetone phospha...

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Detalles Bibliográficos
Autores principales: Hernandez, Arlet, Sonavane, Manoj, Smith, Kelly R., Seiger, Jensyn, Migaud, Marie E., Gassman, Natalie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9725129/
https://www.ncbi.nlm.nih.gov/pubmed/36472985
http://dx.doi.org/10.1371/journal.pone.0278516