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Interpreting and de-noising genetically engineered barcodes in a DNA virus

The concept of a nucleic acid barcode applied to pathogen genomes is easy to grasp and the many possible uses are straightforward. But implementation may not be easy, especially when growing through multiple generations or assaying the pathogen long-term. The potential problems include: the barcode...

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Detalles Bibliográficos
Autores principales: Blois, Sylvain, Goetz, Benjamin M., Bull, James J., Sullivan, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9725130/
https://www.ncbi.nlm.nih.gov/pubmed/36413582
http://dx.doi.org/10.1371/journal.pcbi.1010131