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Interpreting and de-noising genetically engineered barcodes in a DNA virus
The concept of a nucleic acid barcode applied to pathogen genomes is easy to grasp and the many possible uses are straightforward. But implementation may not be easy, especially when growing through multiple generations or assaying the pathogen long-term. The potential problems include: the barcode...
Autores principales: | Blois, Sylvain, Goetz, Benjamin M., Bull, James J., Sullivan, Christopher S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9725130/ https://www.ncbi.nlm.nih.gov/pubmed/36413582 http://dx.doi.org/10.1371/journal.pcbi.1010131 |
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